Paracetamol

There is a limit to the amount of paracetamol that can be safely taken in a 24 hour period. You MUST see your doctor as soon as possible, or call the Poisons Information Line (13 11 26) and go to the nearest emergency department if you think you have taken too much paracetamol.

• For otherwise healthy adults the maximum daily dose is 4 grams per day (6-8 tablets, depending on the strength of the tablets). This may be less if you have severe liver problems, or are frail or elderly.
• Doses for children depend on their weight and must be calculated.
• Be aware that other medicines, like cold and flu remedies and pain medicines might also contain paracetamol. Always check the ingredients before taking them. Make sure not to exceed the recommended daily dose of paracetamol by considering all sources. 
• It is also important to tell your nurse / doctor / pharmacist about any other medicines you are taking.

Paracetamol is usually taken by mouth in tablet or capsule form. It is also available as liquids and rectal suppositories.

What is the dosage?

Paracetamol usually presents as a 500mg tablet or capsule. It is also available as a slow release (SR) 665mg tablets. The usual dose for adults and children 12 years and older is 2 tablets per dose, your doctor will advise on a maximum of 3g or 4g paracetamol per day.

Liquid paracetamol is available for younger children. For over-the-counter paracetamol, the dose depends on the child’s age and weight. Be sure to check the dosage guide on the packaging as liquid paracetamol comes in different strengths.

How often should it be taken?

Paracetamol can be taken when needed, that is when you feel the pain, or it may be taken regularly to manage persistent pain. Regular dosing is recommended to treat the persistent pain that may be associated with arthritis. 

Paracetamol is usually taken every 4 to 8 hours. For arthritis, the dose might be two slow-release tablets every 8 hours, for example, at 8am, 2pm, and bedtime.

Most people who take paracetamol at recommended doses do not have side effects. It also does not increase blood pressure or increase the risk of heart attacks.

Effects associated with overdose 

Paracetamol is very safe when you take the right amount. But because it is found it many different medicines, accidental overdoses can happen if you’re not careful. Severe damage to the liver and kidneys can occur when more than the recommended dose is taken. In some cases, overdosing of paracetamol has caused death. See 'Important things to remember' above.

Dose in liver disease

Paracetamol is broken down in the liver. It is therefore important that you tell your nurse / doctor / pharmacist if you have any liver problems as the dose may need to be reduced.

Use with other medicines

Paracetamol can interact with other medicines. Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins, or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.

Use with alcohol

Paracetamol can be used safely with a moderate intake of alcohol. However, it is best to avoid drinking more than 4 standard drinks at once, even if you don’t do it often. 

Use in pregnancy and breastfeeding

• Store paracetamol in a cool, dry place, away from direct heat and light.
• Keep all medicines out of reach of children.