For the latest COVID information Click Here.
Updated November 2019
Ixekizumab is a medicine to treat active psoriasis and psoriactic arthritis. It may take a number of weeks for you to notice relief of joint pain, swelling and stiffness.
Ixekizumab is injected just under the skin (subcutaneously) of the thigh or abdomen. It is best to avoid (if possible) any areas of skin involved with psoriasis. The prefilled autoinjector or syringe should be taken out of refrigerator 20 minutes before injecting to allow it to reach room temperature. Do not shake or freeze it. It can be injected by your doctor, nurse, carer, or by you. If injecting yourself, be sure to follow the detailed instructions carefully to ensure the best response. It is important to change the injection site each time.
If you forget an injection, make the next injection as soon as you remember and continue to use it as you normally would. Do not inject a double dose to make up for the one you missed. If you have missed more than one dose or are not sure what to do, check with your doctor or pharmacist.
Let your doctor know as soon as possible if you accidentally use more than your prescribed dose. The risk of adverse events is higher with larger doses.
Ixekizumab is an 80mg prefilled syringe or prefilled autoinjector. The usual starting dose is 2 injections, followed by 1 injection every 4 weeks.
Ixekizumab may be taken in combination with other arthritis medicines, including:
There are separate information sheets for the medicines mentioned above.
Treatment can continue with ixekizumab as long as it is effective and you are not experiencing any adverse effects. Your doctor will tell you how long to continue treatment with ixekizumab.
As with most medicines, ixekizumab may cause side effects in some people. You may need medical treatment if you get some side effects. Tell your doctor if you are concerned about any possible side effects.
Other less common side effects include oral thrush, signs of low white cells (such as fever, sore throat or mouth ulcers due to infections), athelete’s foot, ear infections, painful periods, conjunctivitis or discharge from the eye with itching, redness and swelling.
Other side effects not listed in this leaflet may also occur. Tell your doctor if you notice any other side effects that you think might be caused by ixekizumab.
Before treatment is started with ixekizumab, your doctor will examine you for tuberculosis (TB). If your doctor feels that you are at risk for TB, you may be treated with medicine for TB before you begin treatment and during treatment with ixekizumab.